This treatise on the immortality of the soul (Roth Collection 634 and Semitic P-1.39) includes Menasseh’s sermons on the subject. It was printed by his son Samuel in 1652.
This Hebrew work, along with De resurrection mortuorum, was devoted to reinforcing orthodox Jewish belief. Corrections and a postscript were provided by the anti-Kabbalist rabbi and envoy of the King of Morocco, Jacob ben Aaron Sasportas (1610–1698), who also added a Hebrew poem of commendation. Sasportas, then living in Amsterdam in exile from Morocco, may have accompanied Menasseh on his London mission. He became a rabbi in London in 1664-65.